Tag Archives: Scientists of Bihar

ISRO scientist Sabir Alam of Chandrayan-3 fame feels he has miles to go

Chhogra Village (Kathihar District), BIHAR :

Sabir Alam with his wife

It is the story of a young boy who once wanted to take his parents to the moon. However, for Sabir Alam, the journey from a small village in Bihar to the one in which he was associated with ISRO’s Chandrayan Mission 3, Moon was a destiny chiselled with grit.

Sabir Ali’s story began in the Chhoghra village in Katihar district, 350 km from Patna, Bihar. Son of a primary school teacher from Seemanchal – one of India’s most underdeveloped regions – this young boy turned his limitations into challenges and life happened to him.

Sabir’s father, Harun Rashid, knew the value of a good education but often wondered how to make his son rise in life with his meagre earnings. “With my limited earnings and the struggle to secure quality education for him, it was a challenging journey,” Harun says.

Sabir Alam having chai

Sabir joined his father’s school, where learning was born from passion rather than resources.

When Sabir cracked the Jawahar Navodaya Vidyalaya (JNV) entrance exam, it was a monumental moment. JNV was a lifeline, offering free education to talented students from rural areas.

He joined the JNV in Kolasi, Katihar, and after his 10th-grade exams in 2012, he shifted to JNV, Puducherry.

Sabir also enrolled in a coaching program run by Avanti, an NGO in collaboration with Tata Motors, to prepare students for competitive exams like IIT–JEE, the gateway to some of India’s most prestigious engineering institutions.

He graduated with a B.Tech in aerospace engineering from the Indian Institute of Space Science and Technology (IIST) in 2018 and then joined the Indian Space Research Organisation (ISRO) at the Vikram Sarabhai Space Centre, Thiruvananthapuram, Kerala.

Sabir Alam with fellow scientists celebrating the launch of Chandrayaan-3

Then came the day that would forever etch Sabir’s name in history. On August 23, 2023, when India made its historic landing on the moon’s South Pole as part of the Chandrayaan-3 mission, Sabir stood among the brightest minds who made it possible.

The moment was both joyous and emotional for his family.

“It was like Eid for us,” says Harun Rashid. “People gathered at our house to congratulate us and shower blessings. It felt natural as a young man from a region often associated with poverty and underdevelopment contributed to the country’s successful lunar mission,” he says with palpable pride and happiness.

Son of the soil : Sabir Alam in his field in the village

Though his mother, a homemaker, may not fully grasp the enormity of the achievement, she stood in quiet pride, holding back her tears. “As a mother, I cannot put my emotions into words. All I know is that my son has made not just Seemanchal but the entire country proud,” she says, her voice trembling with love and joy.

For the family, Sabir’s rise was not about wealth. “There was no financial investment in his schooling,” his mother said.

Sabir’s education was sustained by the values of hard work, sacrifice, and scholarships. The JNV provided the crucial foundation, and scholarships allowed Sabir to scale the mountain that seemed insurmountable to so many.

Did Sabir’s mother ever imagine he would join ISRO or contribute to such a prestigious national mission? I asked her. “I always knew he would succeed,” she said. “He often joked during his visits home that he would take us to the moon one day.”

Sabir Alam showing a model of the lander at the surface of the moon to his son at ISRO center

Mumtaz Naiyer, a scientist based in the United Kingdom, shares a unique bond with Sabir. Hailing from the same region, he always acknowledged Sabir’s abilities. “Sabir has always been extraordinary. He stands out from other youth in Seemanchal because of his approach, temperament, and determination to learn and succeed. Thanks to Sabir, we, the Surjapuri-speaking (local dialect of the region) people, Seemanchalis and Biharis, are now part of history,” Naiyer says.

“This will certainly inspire the youth of this underdeveloped region to dream big,” Naiyer adds. “I also want to thank Sabir’s parents, as their son has brought immense pride to Seemanchal.”

Yet, despite all his achievements, Sabir has never seen himself as someone extraordinary. In a post on Facebook’s page ‘Humans of Seemanchal’ he wrote, “Honestly, I do not feel that I have achieved anything extraordinary or made any significant breakthrough in my field. I do not need to talk much about Seemanchal – its literacy rate already tells its story. I was just fortunate to find a way around the high cost of education.”

For Sabir, it was never about the prestige of joining ISRO. It is simply a milestone. “There are numerous challenges for those from backward areas, but with dedication, hard work, willpower, and, most importantly, awareness, you can overcome them,” he advises.

source: http://www.awazthevoice.in / Awaz, The Voice / Home> Stories / by Tarique Anwar, New Delhi / February 13th, 2025

Seyed Ehtesham Hasnain: scientist who changed the course of TB diagnosis in India

Gaya, BIHAR:

Prof Seyed Ehtesham Hasnain

Prof Seyed Ehtesham Hasnain’s scientific research has changed the complicated regimen for the diagnosis of Drug-Resistant Tuberculosis and the Indian Basmati getting its patent and trademark in the UK in the fight against the Pakistani variant. This Bihar-born scientists’ findings have saved patients suffering from Drug-Resistant TB money and time and helped the Indian government and farmers earn through exports of the Basmati.

He told Awaz-the Voice in an interview that the government of India has taken at least two major policy decisions based on his research. “One decision was that previously the testing of tuberculosis (TB) was based upon antibody-antigen reaction. So, the antibody formed was based on the antigen of a bacterial protein, and the sequence (genetic) used was mostly European or American isolates. 

“When I did sequencing in India, I found out that the Indian variant is completely different. Therefore, the test could give false positives or negatives…. I published this finding and had a meeting with the DG of ICMR (Indian Council for Medical Research) and recommended that the tests based on foreign kits be banned and that made a big impact.” 

The President, Dr. A.P.J. Abdul Kalam presenting Padma Shri to Prof. Seyed E. Hasnain, renowned biologist, at an Investiture Ceremony at Rashtrapati Bhavan in New Delhi on March 29, 2006.

Padma Shri recipient Seyed Ehtesham Hasnain said. E. Hasnain was awarded the Order of Merit of the Federal Republic of Germany, the highest Civilian decoration of Germany in 2014. Nature, a famous scientific journal, reported on his receiving the award, “With the Order of Merit, he joins the league of outstanding personalities from various fields including Nobel laureate biologist Paul Herman Muller, former German Chancellor Helmut Kohl, former Japanese Prime Minister Yasuhiro Nakasone and music conductor John Crosby.” 

In 2006, he received Padma Shri in recognition of his scientific work. Shanti Swarup Bhatnagar Prize (1995) and J. C. Bose Fellowship (2006), two of the most prestigious Indian Awards in the field of science have also come his way apart from numerous other decorations.

Hasnain was born in Gaya, Bihar in 1954. He was born seven years after India had attained independence. At that time Bihar was not the most developed of the Indian states. Hasnain’s father was a college lecturer and he nursed a dream of studying abroad. He studied at the Nazareth Academy, an expensive school in the town. It’s said that almost 20% of his father’s salary would go into children’s school fees. 

He did his M.Sc. from the Jawaharlal Nehru University in New Delhi. However, though he was selected for his post-graduation studies by Harvard University, for some reason he could not join.

In 1981, Hasnain moved to Canada as a Post-doctoral Fellow (PDF). He worked in Canada and the USA for the next six years. At this stage, his father asked him to return home to serve his country and people. He was advised by many people that he must try to get his green card before moving back to India. 


Seyed Ehtesham Hasnain with Dr Venky Ramakrishna, Nobel Prize Winner and President of Royal Society, UK, in Cambridge

In 1987, he joined the National Institute of Immunology (NII) as a scientist. Hasnain says, “I thought that after getting a green card, I would have a fall-back and a plan B. I did not want a plan B. My plan was the only plan A. I will work in India and do something good in India.”

Hasnain broke the convention by not continuing the research he was doing abroad. He started afresh and soon made a name for himself in research of baculoviruses. He established a baculovirus insect cell expression system (BEVS) for the first time in India and used this to express foreign genes and also to ask fundamental questions concerning gene expression in BEVS. The idea was to make India a scientific power.

Hasnain says that when his career was at the peak with research on baculovirus one day, Dr. Sandeep Basu, the then director of NII, asked him, “Seyed, you are publishing in good journals, it is fine, but how does humanity benefit? What is India gaining out of it? How are the common men benefiting from your papers? Doing research is good but do something which will benefit the common man.” 

This was the turning point in Hasnain’s life and career. He says “I decided to do something where I can do direct application.” He started his research on tuberculosis. 

Seyed Ehtesham Hasnain at the Global Health Conference organized by the German National Academy of Sciences, Leopoldina, Halle, Germany

Hasnain initiated studies on molecular epidemiology and genetics of multi-drug resistant (MDR) M. tuberculosis (M.tb). He says, “second important observation that was published, again the first time in the world. We used to test TB for drug resistance. The bacteria was tested against each drug. I showed with my study that if the bacteria are resistant to one drug then it will be resistant to almost all other drugs. I established the correlation and proposed that you don’t need to do multi-drug resistance testing for all the drugs. Just test one drug rifampicin and if it is confirmed then 95%-99% of drugs will be resisted by the bacteria. That has become a standard treatment all over the world. He is still working on developing cheaper methods of diagnosing TB.

In 1999 Hasnain was invited as the first director of the Centre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad. It was based on his work on Indian Basmati Rice DNA fingerprinting that India won the Patent case against Pakistan enabling the export of the Indian Basmati to the UK. This prevented a major economic loss to India. Subsequently, the Ministry of Commerce established the CDFD-APEDA Basmati DNA Analysis Centre, where all Basmati exports are certified. 

Hasnain also served as Vice Chancellor of the University of Hyderabad (2005-11), and Vice Chancellor of Hamdard University and is currently A National Science Chair of SERB, at the Department of Biochemical Engineering and Biotechnology at IIT-Delhi. 

Hasnain Mantra is: “Nothing is a substitute for hard work.”  

source: http://www.awazthevoice.in / Awaz, The Voice / Home> Story / by Saquib Salim / November 03rd, 2023