Tag Archives: Dr Mumtaz Naiyer – University of Southampton – U.K

ISRO scientist Sabir Alam of Chandrayan-3 fame feels he has miles to go

Chhogra Village (Kathihar District), BIHAR :

Sabir Alam with his wife

It is the story of a young boy who once wanted to take his parents to the moon. However, for Sabir Alam, the journey from a small village in Bihar to the one in which he was associated with ISRO’s Chandrayan Mission 3, Moon was a destiny chiselled with grit.

Sabir Ali’s story began in the Chhoghra village in Katihar district, 350 km from Patna, Bihar. Son of a primary school teacher from Seemanchal – one of India’s most underdeveloped regions – this young boy turned his limitations into challenges and life happened to him.

Sabir’s father, Harun Rashid, knew the value of a good education but often wondered how to make his son rise in life with his meagre earnings. “With my limited earnings and the struggle to secure quality education for him, it was a challenging journey,” Harun says.

Sabir Alam having chai

Sabir joined his father’s school, where learning was born from passion rather than resources.

When Sabir cracked the Jawahar Navodaya Vidyalaya (JNV) entrance exam, it was a monumental moment. JNV was a lifeline, offering free education to talented students from rural areas.

He joined the JNV in Kolasi, Katihar, and after his 10th-grade exams in 2012, he shifted to JNV, Puducherry.

Sabir also enrolled in a coaching program run by Avanti, an NGO in collaboration with Tata Motors, to prepare students for competitive exams like IIT–JEE, the gateway to some of India’s most prestigious engineering institutions.

He graduated with a B.Tech in aerospace engineering from the Indian Institute of Space Science and Technology (IIST) in 2018 and then joined the Indian Space Research Organisation (ISRO) at the Vikram Sarabhai Space Centre, Thiruvananthapuram, Kerala.

Sabir Alam with fellow scientists celebrating the launch of Chandrayaan-3

Then came the day that would forever etch Sabir’s name in history. On August 23, 2023, when India made its historic landing on the moon’s South Pole as part of the Chandrayaan-3 mission, Sabir stood among the brightest minds who made it possible.

The moment was both joyous and emotional for his family.

“It was like Eid for us,” says Harun Rashid. “People gathered at our house to congratulate us and shower blessings. It felt natural as a young man from a region often associated with poverty and underdevelopment contributed to the country’s successful lunar mission,” he says with palpable pride and happiness.

Son of the soil : Sabir Alam in his field in the village

Though his mother, a homemaker, may not fully grasp the enormity of the achievement, she stood in quiet pride, holding back her tears. “As a mother, I cannot put my emotions into words. All I know is that my son has made not just Seemanchal but the entire country proud,” she says, her voice trembling with love and joy.

For the family, Sabir’s rise was not about wealth. “There was no financial investment in his schooling,” his mother said.

Sabir’s education was sustained by the values of hard work, sacrifice, and scholarships. The JNV provided the crucial foundation, and scholarships allowed Sabir to scale the mountain that seemed insurmountable to so many.

Did Sabir’s mother ever imagine he would join ISRO or contribute to such a prestigious national mission? I asked her. “I always knew he would succeed,” she said. “He often joked during his visits home that he would take us to the moon one day.”

Sabir Alam showing a model of the lander at the surface of the moon to his son at ISRO center

Mumtaz Naiyer, a scientist based in the United Kingdom, shares a unique bond with Sabir. Hailing from the same region, he always acknowledged Sabir’s abilities. “Sabir has always been extraordinary. He stands out from other youth in Seemanchal because of his approach, temperament, and determination to learn and succeed. Thanks to Sabir, we, the Surjapuri-speaking (local dialect of the region) people, Seemanchalis and Biharis, are now part of history,” Naiyer says.

“This will certainly inspire the youth of this underdeveloped region to dream big,” Naiyer adds. “I also want to thank Sabir’s parents, as their son has brought immense pride to Seemanchal.”

Yet, despite all his achievements, Sabir has never seen himself as someone extraordinary. In a post on Facebook’s page ‘Humans of Seemanchal’ he wrote, “Honestly, I do not feel that I have achieved anything extraordinary or made any significant breakthrough in my field. I do not need to talk much about Seemanchal – its literacy rate already tells its story. I was just fortunate to find a way around the high cost of education.”

For Sabir, it was never about the prestige of joining ISRO. It is simply a milestone. “There are numerous challenges for those from backward areas, but with dedication, hard work, willpower, and, most importantly, awareness, you can overcome them,” he advises.

source: http://www.awazthevoice.in / Awaz, The Voice / Home> Stories / by Tarique Anwar, New Delhi / February 13th, 2025

Kishanganj born scientist develops Hepatitis-C vaccine in British university

Thakurganj (Kishanganj), BIHAR / Southampton(Hampshire), U.K :

UK research team makes significant discovery on path to develop vaccine against global viruses

It’s very pleasing to know that a major breakthrough happened in the global biological science research and innovation of a life-saving vaccine has Bihar connection. Dr. Mumtaz Naiyer, a postdoctoral scientist at University of Southampton, UK originally hailing from Kishanganj (Bihar) with his team has made a significant discovery in efforts to develop a vaccine against Zika, dengue and Hepatitis C viruses that affect millions of people around the world. In a study published in Science Immunology, researchers have shown that natural killer cells (NK cells), which are a fundamental part of the body’s immune system, can recognise many different viruses including global pathogens such as Zika, dengue and Hepatitis C viruses, through a single receptor called KIR2DS2.

A native of Thakurganj (Kishanganj), Dr. Mumtaz Naiyer, the first author of the paper, said: “This is a well-presented study and a significant advancement in this field that identifies the important role of the receptor KIR2DS2. Since I come from India, which has thousands of cases of dengue each year, I can understand the suffering of patients with dengue. Nothing would give me greater pleasure than to ease the suffering of these dengue-affected patients.”

The study, which was funded by the Wellcome Trust and the Medical Research Council, analysed DNA from more than 300 patients exposed to the Hepatitis C virus, which showed that the KIR2DS2 receptor was associated with successfully clearing the virus.  The team then identified that the immune system targeted the NS3 helicase protein of this using the receptor and found that it prevented the virus multiplying. They went on to demonstrate that this same mechanism could be important for many different viruses for example the Zika and dengue viruses, which also contain a region within their NS3 helicase protein that is recognised by the KIR2DS2 receptor.

The researchers now need to determine whether these KIR2DS2+ NK cells are protective during acute flaviviral infections, and are hoping to develop a vaccine that targets natural killer cells.  They believe that a similar process could be used to target cancer.

Lead researcher Salim Khakoo, Professor of Hepatology, said the findings are very exciting and could change the way viruses are targeted by vaccines but warned that the research is still at an early stage, and animal studies/clinical trials will be needed to test the findings.

Professor Khakoo added: “Cancer treatments that use the body’s own immune system are becoming more common. Our findings present a completely new strategy for virus therapeutics which could be easily translated into the field of cancer. The next few years are going to be very exciting in this field.”

The research paper can be accessed by here: http://immunology.sciencemag.org/lookup/doi/10.1126/sciimmunol.aal5296

source: http://www.milligazette.com / The Milli Gazette / Home> News> Science & Technology / by The Milli Gazette Online / October 02nd, 2017