Prof. Qudsia Tahseen, Department of Zoology at Aligarh Muslim University has been named as the National Committee representative for the International Union of Biological Sciences (IUBS), announced by the Indian National Science Academy (INSA).
Commencing her three-year term on January 1 this appointment emphasizes Prof. Qudsia’s contributions to the fields of Taxonomy and Biodiversity. She has the distinction of holding fellowships in all three prestigious National Academies.
The IUBS, founded in 1919, is a global non-profit organization dedicated to facilitating and coordinating biological research worldwide. Its mission spans diverse areas, with the goal of addressing global biological challenges. Prof. Qudsia’s appointment to the newly formed INSA National Committee for IUBS, consisting of seven experts, solidifies her role as a representative for India in the realm of biological sciences.
Prof. Qudsia while acknowledging her appointment said the committee, serving as the national arm of IUBS, is pivotal in advancing IUBS initiatives at a domestic level. This includes policy advocacy, tackling global challenges, setting research priorities, fostering collaborations, and promoting the sustainable use of biological resources.
source: http://www.timesofindia.indiatimes.com / The Times of India / Home> News> India News / by TNN (headline edited) / January 05th, 2024
In a big breakthrough in the field of cancer prevention, Dr Hifzur Rahman Siddique, Department of Zoology, Aligarh Muslim University, in coordination with Dr. Keigo Machida, University of South California, USA, has discovered a common mechanism that activates disruption of a single RNA binding protein, MSI-2 binding to mRNAs of the cancer-causing proteins and significantly reduces the synthesis and accumulation of these proteins, reducing HCV infection and proliferation. The single RNA binding protein (named MSI-2) helps to accumulate multiple cancer-causing proteins in patients and helps to proliferate Hepatitis C Virus to promote liver cancer.
Dr. Siddique and the team who have identified this protein by analyzing the liver tissues of 374 liver cancer patients, said, “As we know, alcohol and cholesterol-rich high-fat diet and hepatitis infection promotes cancer initiation, but the exact molecular mechanism is unknown. In this research work, we have discovered that MSI-2 protein helps to accumulate multiple cancer-causing proteins and supports HCV proliferation to aggravate the disease.”
Dr Siddique said that Liver hyperplasia is also reduced in the animal model predisposed to viral infection fed with alcohol mixed cholesterol-rich high-fat diet. This is a very exciting discovery and could serve as a potential therapeutic target for the drug design and give direction to the management strategy for this deadly disease.
“The study has been recently published in Cell Death Discovery (April 2023, available at www.nature.com/cddiscovery),” he added.
Dr Siddique and his team had earlier discovered the molecular pathway that promotes the abnormal division of Cancer Stem Cells that are responsible for cancer therapy failure and Cancer reappearance/recurrence. Their study was then published in the prestigious journal Nature Communications 11 (2020) and found a place in different national and international dailies.
He said that the liver is considered the powerhouse of the body and due to the change in lifestyle, chronic alcohol consumption, high-fat diet, and hepatitis virus infection, the incidence of liver cancer is increasing fast. More than 350 million people are currently infected with hepatitis viruses, out of which 70 million are infected with Hepatitis C. It is estimated that approximately 40 million people are chronically infected with Hepatitis B and 6-12 million people with Hepatitis C. The situation worsens when Hepatitis infection occurs in an alcoholic person.
He said that the discovery is significant in the treatment of liver cancer as blocking the identified protein has an immense effect on liver cancer in the animal model and also stops the accumulation of the number of human cancer-causing proteins, the proliferation of hepatitis viruses and improving recovery.
Dr Siddique has been working on Cancer Stem Cells for a decade and has established a dedicated lab to initiate pioneer research on Cancer Stem Cells at AMU with a team of 10 researchers and collaborators from the USA, Russia, China, the UK, India, etc.
Recently, he got a Patent for his herbal formulation to prevent liver cancer and expecting some extramural grant from the Government of India for further clinical research.
source: http://www.amu.ac.in / Aligarh Muslim University – AMU / Home> AMU News / by Public Relations Office / May 01st, 2023
Prof Nafees Ahmad Khan, Department of Botany, Aligarh Muslim University, has been declared as the Elected Fellow of the National Academy of Sciences, India (NASI).
The National Academy of Sciences, recognises researchers who excel in the field of their research as Fellow of the Academy, which is considered as the most coveted accomplishment in academics.
Prof Khan has worked on the mechanisms of hormonal and nutritional regulation of plant development with emphasis on plant resilience against stressful environments using nutriomics and metabolomics.
He has published many research papers in crucial high Impact Factors journals and collaborated internationally for research. He has published about 200 research papers（H-index 67; i–10 index 175）and was noted as one of the most-cited Indian researchers in the area of Plant Science by Elsevier every year from 2019 to 2022.
He has edited 19 books published by Elsevier, Springer-Nature, Frontiers, NOVA, Alpha Science and others. Supervised research projects focused on signalling molecules-nutriomics and abiotic stress tolerance mechanisms, and served as Editor/Guest Editor of the leading plant science journals, published by Elsevier, Frontiers, Springer-Nature MDPI.
Prof Khan is also fellow of The Linnean Society, Indian Botanical Society, Indian Society for Plant Physiology.
source: http://www.amu.ac.in / Aligarh Muslim University / Home / by Public Relations Office / November 04th, 2022
